abstract：BACKGROUND:Immune responses play a key role in the pathogenesis and progression of polypoidal choroidal vasculopath (PCV) and age-related macular degeneration (AMD). In this study, we determined the Th cell-associated immune responses by measuring the cytokine expression of peripheral blood mononuclear cells (PBMC) in ...

journal_title：BMC ophthalmology

authors： Yu Y,Ren XR,Wen F,Chen H,Su SB

更新日期：2016-06-07 00:00:00

abstract：BACKGROUND:To investigate the accommodative loads change needed to maintain binocular fusion in patients with intermittent exotropia (IXT). METHODS:Seventeen consecutive patients with basic IXT and 15 normal controls were recruited. The WAM-5500 autorefractor (GrandSeiko, Fukuyama, Japan) was used to measure refractiv...

journal_title：BMC ophthalmology

authors： Ha SG,Jang SM,Cho YA,Kim SH,Song JS,Suh YW

更新日期：2016-06-07 00:00:00

abstract：BACKGROUND:Although the association between metabolic syndrome and intraocular pressure is well known, the relationship between the intraocular pressure and different combination of the components of metabolic syndrome has not been actively researched yet. The study aimed to investigate the relationship between the int...

journal_title：BMC ophthalmology

authors： Son J,Koh H,Son J

更新日期：2016-06-06 00:00:00

abstract：BACKGROUND:We report the enhanced depth imaging optical coherence tomography (EDI-OCT) characteristics and variations in a patient with subretinal fluid secondary to a carotid cavernous fistula. CASE PRESENTATION:A 59-year-old man presented with blurred vision in his right eye. Venous congestion of the epiescleral and...

journal_title：BMC ophthalmology

authors： Rey A,Castillo L,Dyrda A,Maseras X,Jürgens I

更新日期：2016-05-26 00:00:00

abstract：BACKGROUND:We explore and compare the advantages and disadvantages of different operating methods for a peripheral iridectomy (PI) for phakic posterior chamber implantable contact lens (ICL) implantation in patients with dark-brown irides. METHODS:Forty-six patients completed this prospective comparative study. Neodym...

journal_title：BMC ophthalmology

authors： Wu Y,Han F,Quan Y,Jiang W,Zhang H,Luo T

更新日期：2016-05-05 00:00:00

abstract：BACKGROUND:Differences in the increase in matrix metalloproteinase (MMP) and decrease in tissue inhibitor of metalloproteinase (TIMP) activity may contribute to the different characteristics observed clinically on decreased intraocular pressure in patients with glaucoma or ocular hypertension. The purpose of this study...

journal_title：BMC ophthalmology

authors： Yamada H,Yoneda M,Gosho M,Kato T,Zako M

更新日期：2016-03-08 00:00:00

abstract：BACKGROUND:Central Serous Chorioretinopathy (CSC) has been previously reported as an infrequent complication of pregnancy that usually resolves spontaneously after delivery, with minimal or no sequel. We report a case of a severe form of CSC in an uncomplicated pregnancy with extensive subfoveal exudates and severe per...

journal_title：BMC ophthalmology

authors： Maggio E,Polito A,Freno MC,Pertile G

更新日期：2015-12-22 00:00:00

abstract：:Although the mechanism of dry eye disease is not clearly understood, it is certain that inflammation and the immune response play a major role in determining the health of the ocular surface in dry eye patients. Accurate ocular surface characterization during the early stages of dry eye disease is critical for success...

journal_title：BMC ophthalmology

authors： Na KS,Hwang KY,Lee HS,Chung SH,Mok JW,Joo CK

更新日期：2015-12-17 00:00:00

abstract：:Conjunctival and subconjunctival fibrogenesis and inflammation are sight compromising side effects that can occur subsequent to glaucoma filtration surgery. Despite initial declines in intraocular pressure resulting from increasing aqueous outflow, one of the activated responses includes marshalling of proinflammatory...

journal_title：BMC ophthalmology

authors： Yamanaka O,Kitano-Izutani A,Tomoyose K,Reinach PS

更新日期：2015-12-17 00:00:00

abstract：:Mucins locate to the apical surfaces of all wet-surfaced epithelia including ocular surface. The functions of the mucins include anti-adhesive, lubrication, water retention, allergens and pathogen barrier function. Ocular surface pathologies, i.e. dry eye syndrome or allergic conjunctivitis, are reportedly associated ...

journal_title：BMC ophthalmology

authors： Shirai K,Saika S

更新日期：2015-12-17 00:00:00

abstract：:Meibomian gland dysfunction (MGD) is the major cause of evaporative dry eye disease (EDED) and dysfunction is widely thought to mechanistically involve ductal hyperkeratinization, plugging and obstruction. This review re-evaluates the role of hyperkeratinization in MGD based on more recent findings from mouse models. ...

journal_title：BMC ophthalmology

authors： Jester JV,Parfitt GJ,Brown DJ

更新日期：2015-12-17 00:00:00

abstract：BACKGROUND:Glaucoma is a progressive disease responsible for the second commonest cause of blindness in the UK. Identifying appropriate patients for hospital care remains an ongoing challenge for all UK hospital glaucoma services. The purpose of our study is to evaluate accuracy and outcome of community optometry refer...

journal_title：BMC ophthalmology

authors： El-Assal K,Foulds J,Dobson S,Sanders R

更新日期：2015-12-07 00:00:00

abstract：BACKGROUND:Previous studies described cases of Ocriplasmin injections in patients with vitreo-macular traction and reduced central visual acuity. We describe the first case of a patient with 20/20 visual acuity and vitreo-macular traction treated with Ocriplasmin, and, for the first time in literature, we evaluated the...

journal_title：BMC ophthalmology

authors： Rossi S,Orrico A,Melillo P,Testa F,Simonelli F,Della Corte M

更新日期：2015-10-29 00:00:00

abstract：BACKGROUND:The aim of this study was to prove the relationship between the intraocular straylight level and diabetic retinopathy (DR) according to disease severity. Also, we aimed to evaluate whether diabetes mellitus (DM) per se could be a risk factor of increased intraocular straylight although we did not rely on a d...

journal_title：BMC ophthalmology

authors： Hwang HB,Yim HB,Chung SK

更新日期：2015-10-13 00:00:00

abstract：BACKGROUND:Suture exposure remains to be a potential problem of transscleral fixated posterior chamber intraocular lens (PCIOL). We report a modified technique to minimize the risk of suture exposure for the transscleral fixation of PCIOL. METHODS:The modified surgical technique is as following: at first, two 3 mm × 4...

journal_title：BMC ophthalmology

authors： Long C,Wei Y,Yuan Z,Zhang Z,Lin X,Liu B

更新日期：2015-10-02 00:00:00

abstract：BACKGROUND:Central corneal thickness (CCT) measurement has become an important test in the diagnosis and management of glaucoma. Currently, ultrasound corneal thickness measurement (pachymetry) is the most frequently used clinical technique and the gold standard to assess CCT. Newer instruments are currently available ...

journal_title：BMC ophthalmology

authors： Ayala M,Strandås R

更新日期：2015-09-29 00:00:00

abstract：BACKGROUND:To evaluate the long-term outcomes of Argon laser photocoagulation compared to surgical direct cyclopexy in small-size cyclodialysis cleft patients. METHODS:This is a retrospective study. Small-size cyclodialysis cleft patients who underwent Argon laser photocoagulation and surgical direct cyclopexy were re...

journal_title：BMC ophthalmology

authors： Han JC,Kwun YK,Cho SH,Kee C

更新日期：2015-09-24 00:00:00

abstract：BACKGROUND:To compare scleral buckling (SB) and pars plana vitrectomy (PPV) using a wide angle viewing system (WAVS) for uncomplicated phakic rhegmatogenous retinal detachment (RRD). METHODS:The medical records of patients with uncomplicated phakic RRD were retrospectively reviewed. Eyes with pseudophakic or attached ...

journal_title：BMC ophthalmology

authors： Park SW,Kwon HJ,Kim HY,Byon IS,Lee JE,Oum BS

更新日期：2015-09-11 00:00:00

abstract：BACKGROUND:To report a case of late closure of idiopathic full-thickness macular hole (FTMH) after vitrectomy with the inverted internal limiting membrane (ILM) technique. CASE PRESENTATION:A 68-year-old lady with a stage IV FTMH underwent pars plana vitrectomy with 25 gauge plus transconjunctival system, ILM peeling ...

journal_title：BMC ophthalmology

authors： Chung CY,Wong DS,Li KK

更新日期：2015-08-26 00:00:00

abstract：BACKGROUND:Artificial iris anterior chamber implants were originally developed for therapeutic purposes but have been used recently for the cosmetic alteration of eye colour. There is a growing body of evidence surrounding their associated risks. We report a case presenting with complications secondary to bilateral New...

journal_title：BMC ophthalmology

authors： Shweikh Y,Ameen S,Mearza A

更新日期：2015-08-08 00:00:00

abstract：BACKGROUND:The effectiveness of ranibizumab in the treatment of diabetic macular edema has been proven with large clinical trials. For bevacizumab only two clinical trials have been published and a head-to-head comparison is lacking to date. However, if proved non-inferior to ranibizumab, use of the off-label bevacizum...

journal_title：BMC ophthalmology

authors： Schauwvlieghe AM,Dijkman G,Hooymans JM,Verbraak FD,Hoyng CB,Dijkgraaf MG,Van Leeuwen R,Vingerling JR,Moll AC,Schlingemann RO

更新日期：2015-07-07 00:00:00

abstract：BACKGROUND:we conducted our meta-analysis of published studies to assess existing evidence about the efficacy and safety of vitrectomy with ILM peeling vs. that of vitrectomy with no ILM peeling for Macular hole-induced retinal detachment. METHODS:Databases, including Pubmed, Cochrane Library, Ovid, Web of Science, Wa...

journal_title：BMC ophthalmology

authors： Su J,Liu X,Zheng L,Cui H

更新日期：2015-06-20 00:00:00

abstract：BACKGROUND:This objective of the review and analysis is to demonstrate that acyclovir (ACV) 3% ophthalmic ointment is superior to idoxuridine (IDU) in treating herpetic keratitis (HK) presenting as dendritic and geographic ulcer sub-types. METHODS: DATA SOURCES:Publications in human subjects were identified by search...

journal_title：BMC ophthalmology

authors： Balderson DE,Cai G,Fries MA,Kleinman DM,McLaughlin MM,Trivedi TM,Wurzelmann JI,Young SB

更新日期：2015-04-17 00:00:00

abstract：BACKGROUND:Docetaxel is a chemotherapeutic agent of the taxane class of drugs for the treatment of breast cancer. We present a female patient who noted decreased vision after docetaxel treatment. CASE PRESENTATION:A 45-year-old female patient received docetaxel treatment after resection of a breast carcinoma. Fundusco...

journal_title：BMC ophthalmology

authors： Enzsoly A,Kammerer K,Nemeth J,Schneider M

更新日期：2015-03-29 00:00:00

abstract：BACKGROUND:The presence of an intraocular cilium is very rare and the response of the eye to the cilium is variable. We present the case of a patient with a cilium found in the vitreous cavity during vitrectomy for rhegmatogenous retinal detachment 40 years following penetrating eye injury. To our knowledge, this is th...

journal_title：BMC ophthalmology

authors： Dettoraki M,Andreanos K,Davou S,Nomikarios N,Moschos MM,Brouzas D

更新日期：2015-03-12 00:00:00

abstract：BACKGROUND:To investigate machine learning methods, ranging from simpler interpretable techniques to complex (non-linear) "black-box" approaches, for automated diagnosis of Age-related Macular Degeneration (AMD). METHODS:Data from healthy subjects and patients diagnosed with AMD or other retinal diseases were collecte...

journal_title：BMC ophthalmology

authors： Fraccaro P,Nicolo M,Bonetto M,Giacomini M,Weller P,Traverso CE,Prosperi M,OSullivan D

更新日期：2015-01-27 00:00:00

abstract：BACKGROUND:To report clinical features and risk factors of post-cataract surgery endophthalmitis (PE) due to Stenotrophomonas maltophilia. METHODS:A retrospective case review from December 10, 2010 to April 7, 2011 was performed at the Eye & ENT Hospital, Fudan University. Data were collected for surgical details, dis...

journal_title：BMC ophthalmology

authors： Ji Y,Jiang C,Ji J,Luo Y,Jiang Y,Lu Y

更新日期：2015-01-24 00:00:00

abstract：BACKGROUND:Retinal artery occlusion caused by myxoma is relatively rare. There are several points that should be taken into consideration to avoid overlooking this disorder. CASE PRESENTATION:This case report describes a 43-year-old woman with sudden vision loss in her left eye for 20 days after single sudden syncope....

journal_title：BMC ophthalmology

authors： Yu Y,Zhu Y,Dong A,Su Z

更新日期：2014-12-23 00:00:00

abstract：BACKGROUND:Characterization of the neuro-glial profile of cells growing out of human idiopathic epiretinal membranes (iERMs) and testing their proliferative and pluripotent properties ex vivo is needed to better understand the pathogenesis of their formation. METHODS:iERMs obtained during uneventful vitrectomies were ...

journal_title：BMC ophthalmology

authors： Andjelić S,Lumi X,Yan X,Graw J,Moe MC,Facskó A,Hawlina M,Petrovski G

更新日期：2014-12-23 00:00:00

abstract：BACKGROUND:This study evaluates the efficacy and tolerability (ie, occurrence and severity of hyperemia) of bimatoprost 0.01% in treatment-naïve patients with open-angle glaucoma (OAG) or ocular hypertension in the Korean clinical setting. METHODS:In this multicenter, open-label, observational study, treatment-naïve p...

journal_title：BMC ophthalmology

authors： Park KH,Simonyi S,Kim CY,Sohn YH,Kook MS

更新日期：2014-12-17 00:00:00

abstract：BACKGROUND:Lateralization of horizontal semicircular canal benign paroxysmal positional vertigo (HSC-BPPV) is very important for successful repositioning. The directions of lying-down nystagmus (LDN) and head-bending nystagmus (HBN) have been used as ancillary findings to identify the affected sites. This retrospective...

journal_title：BMC ophthalmology

authors： Oh JH,Song SK,Lee JS,Choi JC,Kang SY,Kang JH

更新日期：2014-11-20 00:00:00

abstract：BACKGROUND:Monocular infantile blindness may be associated with bilateral horizontal nystagmus, a subtype of fusion maldevelopment nystagmus syndrome (FMNS). Patients often adopt a significant anomalous head posture (AHP) towards the fixing eye in order to dampen the nystagmus. This clinical entity has also been report...

journal_title：BMC ophthalmology

authors： Sturm V,Hejcmanova M,Landau K

更新日期：2014-11-20 00:00:00

abstract：BACKGROUND:This case report describes a patient with chronic unilateral chemosis, likely due to treatment with amlodipine besylate. CASE PRESENTATION:A 52-year-old man visited the clinic with symptoms of foreign body sensation and puffiness in his right eye, which had persisted for 4 months. There were no other sympto...

journal_title：BMC ophthalmology

authors： Kim KH,Kim WS

更新日期：2014-10-21 00:00:00

abstract：BACKGROUND:Highly aggressive Burkitt lymphoma (BL) with rapidly progressive painful proptosis of the right eye is rarely encountered. CASE PRESENTATION:A 31-year-old Caucasian female presented with rapidly progressive painful proptosis of the right eye and poor visual acuity. Diagnostic Computer tomography, magnetic r...

journal_title：BMC ophthalmology

authors： Alexander C,George C,Tinatin J,Maia S,Maia M,Mitrofanis P

更新日期：2014-09-08 00:00:00

abstract：BACKGROUND:Combined branch retinal artery and central retinal vein occlusion is a rare condition that has been infrequently reported. This case report, aside from reporting the above-mentioned condition, highlights the importance of performing spectral domain optical coherence tomography in establishing a complete diag...

journal_title：BMC ophthalmology

authors： Karapetyan A,Ouyang P,Tang LS,Zeng J,Ying MD

更新日期：2014-07-12 00:00:00

abstract：BACKGROUND:Fungal keratitis is difficult to treat that can result in corneal blindness requiring penetrating keratoplasty and in fungal endothalmitis. We report a case of fungal keratitis and onychomycosis simultaneously infected by Trichophyton. CASE PRESENTATION:A 77-year old male presented with ocular pain, conjunc...

journal_title：BMC ophthalmology

authors： Jin KW,Jeon HS,Hyon JY,Wee WR,Suh W,Shin YJ

更新日期：2014-07-11 00:00:00

abstract：BACKGROUND:To describe the spectral domain optical coherence tomography (SD-OCT) findings of a patient who developed pigmentary retinopathy following high-dose deferoxamine administration. CASE PRESENTATION:A 34-year-old man with thalassemia major complained of nyctalopia and decreased vision following high-dose intra...

journal_title：BMC ophthalmology

authors： Wu CH,Yang CP,Lai CC,Wu WC,Chen YH

更新日期：2014-07-02 00:00:00

abstract：BACKGROUND:To compare the long-term efficacy of ranibizumab versus bevacizumab for myopic choroidal neovascularization (CNV). METHODS:This was a retrospective, multicenter, comparative, non-randomized study of 64 consecutive patients with myopic CNV treated with ranibizumab (22 patients) or bevacizumab (42 patients). ...

journal_title：BMC ophthalmology

authors： Cha DM,Kim TW,Heo JW,Woo SJ,Park KH,Yu HG,Chung H

更新日期：2014-05-21 00:00:00

abstract：BACKGROUND:To gain more insight into genetic causes of cerebral visual impairment (CVI) in children and to compare ophthalmological findings between genetic and acquired forms of CVI. METHODS:The clinical data of 309 individuals (mainly children) with CVI, and a visual acuity ≤ 0.3 were analyzed for etiology and ocula...

journal_title：BMC ophthalmology

authors： Bosch DG,Boonstra FN,Willemsen MA,Cremers FP,de Vries BB

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Few reports have described the ophthalmic complications that occur after maxillary orthognathic surgery. Since cases of decreased reflex tearing after maxillary orthognathic surgery are extremely rare, we describe 2 cases of loss of reflex tearing after maxillary orthognathic surgery. CASE PRESENTATION:Two ...

journal_title：BMC ophthalmology

authors： Kang S,Jang SY,Lee A,Jang JW

更新日期：2014-03-28 00:00:00